Installing the spamass-milter-postfix package changes the default behaviour of spamass-milter to be more Postfix-friendly, i.e.: The Unix-domain socket used for MTA communication is changed to /var/run/spamass-milter/postfix/sock, and that socket is writable by the postfix group. To configure Postfix to use the milter, add to /etc/postfix/main.cf: smtpd_milters = unix:/var/run/spamass-milter/postfix/sock For further information, see: http://www.postfix.org/MILTER_README.html