Udev rules should be patched for OpenRGB to read/write to I2C devices (i.e. Aura DRAM's). Group 'i2c' does not exists in ArchLinux, there is no 'uaccess' for those devices and there should NOT be: I2C devices should only be accessible to a high-level users group for security reasons.
IMHO you could remove 'plugdev' assignments altogether (since we have 'uaccess' there), replace 'i2c' group with 'wheel' and chmod 660 the devices. This is how I fixed it on my workstation:
$ cat /etc/udev/rules.d/custom-i2c.rules
KERNEL=="i2c-[0-99]*", GROUP="wheel", MODE="0660"
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